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CAS No. : [2734004-61-4]
Synonyms : Isavuconazole impurity 33
IUPAC Name : 1-Methyl-1,4-dihydro-2H-pyrido[2,3-d][1,3]oxazin-2-one
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 250MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 500MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C8H8N2O2 | Mol. Weight : 164.16 |
Appearance : Off-white solid | Melting Point : Not available |
Solubility : MeOH | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an impurity of Isavuconazole, which is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis, which disrupts fungal membrane structure and function. Isavuconazole also acts as a moderate inhibitor of CYP3A4.
References : Seifert H. et al.: Antimicrob Agents Chemother., 51(5), 1818-21, 2007; Steinmann J. et al.: Antimicrob Agents Chemother., 60(11), 6890-6891, 2016; Donnelley M. A. et al.: Infect Drug Resist., 9, 79-86, 2016; Box H. et al.: Antimicrob Agents Chemother., 60(1), 278-87, 2015; Livermore J. et al.: Expert Opin Drug Metab Toxicol., 8(6), 759-65, 2012.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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