Isavuconazole thioamide mixture of isomers

SL-9552

Isavuconazole thioamide mixture of isomers, >98%

CAS No. : [2517755-29-0]

IUPAC Name : 3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide

Price And Availability
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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a racemic thiomide mixture of Isavuconazole, which is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis, which disrupts fungal membrane structure and function. Isavuconazole also acts as a moderate inhibitor of CYP3A4.

References : Seifert H. et al.: Antimicrob Agents Chemother., 51(5), 1818-21, 2007; Steinmann J. et al.: Antimicrob Agents Chemother., 60(11), 6890-6891, 2016; Donnelley M. A. et al.: Infect Drug Resist., 9, 79-86, 2016; Box H. et al.: Antimicrob Agents Chemother., 60(1), 278-87, 2015; Livermore J. et al.: Expert Opin Drug Metab Toxicol., 8(6), 759-65, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.