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iso-Nadolol (tert-butyl-d9)

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SL-8537

iso-Nadolol (tert-butyl-d9), >98%

CAS No. : [1246820-10-9]

IUPAC Name : 6-(2-Hydroxy-3-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)amino)propoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol

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Chemical Properites
Mol. Formula :
C17H18D9NO4
Mol. Weight :
318.46
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version analog of Nadolol, which is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research.

References : von Alvensleben J. C. et al.: Pediatr Cardiol., 38(3), 525-530, 2017; Abe O. et al. Eur J. Clin Pharmacol., 74(6), 775-783, 2018; Vegas O. et al.: Behav Brain Res., 205(1), 200-6, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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