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Iso sildenafil-d3 (methyl-d3)

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SL-1560

Iso sildenafil-d3 (methyl-d3), >98% (CP)

Isotopic Purity : 99 atom % D

CAS No. : [1794829-17-6]

Related CAS No. : [253178-46-0] of the unlabelled compound

Synonyms : 1-[[3-(4,7-Dihydro-2-methyl-7-oxo-3-propyl-2H- pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-d3 piperazine

IUPAC Name : 5-[2-Ethoxy-5-[(4-methyl-d3 1-piperazinyl)sulfonyl]phenyl]-2,6-dihydro-2-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one

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Chemical Properites
Mol. Formula :
C22H27D3N6O4S
Mol. Weight :
477.59
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Iso sildenafil-d3 is an isomer and deuterium labelled version of Sildenafil methylated at N-2 position of the pyrazolo[4,3-d]pyrimidin-7-one nucleus, which is an orally active selective type 5 cGMP phosphodiesterase inhibitor.

References : Wang Z. et al.: J. Sex. Med., Nov, 10(11), 2790-2797, 2013; Li B. B. et al.: Chin. Med., J. (Engl). Sep, 124(17), 2733-2740, 2011; Moretti R. et al.: J. Neuroinflammation. Apr 28, 13(1), 95, 2016; Korkmaz M. F. et al.: Balkan Med. J. Mar, 33(2), 204-211, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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