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Itopride-d6 hydrochloride

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SL-9556

Itopride-d6 hydrochloride, >98%

CAS No. : [1346601-02-2]

Related CAS No. : [122892-31-3] of the unlabelled compound

Synonyms : HSR803-d6 hydrochloride

IUPAC Name : N-(4-(2-(Bis(methyl-d3)amino)ethoxy)benzyl)-3,4-dimethoxybenzamide hydrochloride

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Chemical Properites
Mol. Formula :
C20H20D6N2O4 • HCl
Mol. Weight :
400.93
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Itopride hydrochloride, which is a dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. It enhances gastric motility through both antidopaminergic and anti-acetylcholinesterase mechanisms, and may be used as a gastrointestinal prokinetic agent. Itopride hydrochloride is also used in research related to gastro-esophageal reflux disease (GERD).

References : Iwanaga Y. et al.: Gastroenterology 99(2), 401-8, 1990; Kim Y. S. et al.: World J. Gastroenterol., 11(27), 4210-4, 2005; Hyun C. L. et al.: Yonsei Med J. 49(3), 472-8, 2008; Kenjiro M. et al.: Biol. Pharm. Bull., 31(10), 1917-22, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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