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Ivabradine-d3 N-oxide

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SL-6264

Ivabradine-d3 N-oxide, >98% (HPLC)

Isotopic Purity : 99 atom % D

IUPAC Name : 3-(7,8-Dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-(methyl-d3)propan-1-amine oxide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C27H33D3N2O6
Mol. Weight :
487.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ivabradine-d3 N-oxide is a deuterium labelled version an impurity or metabolite of Ivabradine, which is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.

References : Thollon C. et al.: Br. J. Pharmacol.,112(1), 37-42, 1994; Fang Y. et al.: J. Cardiovasc Pharmacol., 59(3), 260-7, 2012; Kroller-Schon S. et al.: Basic Res Cardiol.,106(6), 1147-58, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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