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Ivabradine-d6 (7,8-dimethoxy-d6) hydrochloride

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SL-6260

Ivabradine-d6 (7,8-dimethoxy-d6) hydrochloride, >98% (HPLC)

Isotopic Purity : 99 atom % D

CAS No. : [2070009-63-9]

IUPAC Name : (S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-bis(methoxy-d3)-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride

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Chemical Properites
Mol. Formula :
C27H30D6N2O5 . HCl
Mol. Weight :
511.09
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ivabradine-d6 is a deuterium labelled version of Ivabradine, which is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.

References : Thollon C. et al.: Br. J. Pharmacol.,112(1), 37-42, 1994; Fang Y. et al.: J. Cardiovasc Pharmacol., 59(3), 260-7, 2012; Kroller-Schon S. et al.: Basic Res Cardiol.,106(6), 1147-58, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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