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JAB-3068

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SI-7056

JAB-3068, >98% (HPLC)

CAS No. : [2169223-48-5]

Synonyms : SHP2-IN-6

IUPAC Name : (S)-1-(4-((3-Amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl)thio)-3,3-difluoroindolin-1-yl)ethan-1-one

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Chemical Properites
Mol. Formula :
C22H26F2N6O2S
Mol. Weight :
476.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : JAB‑3068 is a potent SHP2 inhibitor with an IC50 of 25.8 nM. Its activity profile makes it a useful tool for probing SHP2‑dependent oncogenic signaling.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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