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JAK-IN-33

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SI-7411

JAK-IN-33, >98% (HPLC)

CAS No. : [3032404-49-9]

IUPAC Name : (R)-1-Methoxypropan-2-yl 2-(6-((5-carbamoyl-4-((2-methoxyphenyl)amino)pyridin-2-yl)amino)pyridin-3-yl)acetate

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Chemical Properites
Mol. Formula :
C24H27N5O5
Mol. Weight :
461.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : JAK‑IN‑33 is a Janus kinase (JAK) inhibitor used as a research tool compound for studying JAK‑dependent inflammatory and immune signaling pathways. It provides targeted modulation of the JAK/STAT axis, supporting mechanistic investigations in disease models where JAK activity is dysregulated.

References : Thoma G. et al.: J. Med. Chem., 66(21), 15042-15053, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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