JBJ-04-125-02

SI-7970

JBJ-04-125-02, >98% (HPLC)

CAS No. : [2060610-53-7]

IUPAC Name : 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxo-6-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)-N-(thiazol-2-yl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : JBJ‑04‑125‑02 is an orally active allosteric EGFR inhibitor that selectively targets mutant EGFR, showing sub‑nanomolar potency against EGFR^L858R/T790M. It inhibits downstream signaling from the EGFR^L858R/T790M/C797S triple‑mutant and reduces cancer cell proliferation, supporting its use in antitumor research.

References : To C. et al.: Cancer Discov., 9(7), 926-943, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.