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JH-530

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SI-7974

JH-530, >98% (HPLC)

CAS No. : [2928616-74-2]

IUPAC Name : 6-Bromo-N-(2-methoxy-4-((5-(methylthio)-2-(piperazin-1-yl)pyrimidin-4-yl)amino)phenyl)picolinamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H24BrN7O2S
Mol. Weight :
530.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : JH-530 induces methuosis by promoting large‑scale vacuole formation within TNBC cells, leading to inhibition of cell growth. Its capacity to activate this non‑canonical cell‑death mechanism underlies its antitumor effects and supports its use in cancer biology studies.

References : He J. et al.: J. Med. Chem., 66(11), 7421-7437, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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