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JIN15289

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SI-918

JIN15289, >98% (HPLC)

CAS No. : [2095515-38-9]

Synonyms : RIP1-​IN-​22

IUPAC Name : (S)-3-(2-Benzyl-3-chloro-7-oxo-4,5-dihydro-2H-pyrazolo[3,4-c]pyridin-6(7H)-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepine-8-carbonitrile

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5MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Back Order  Estimated to ship on 01 November 2026
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Note: JIN15289 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We will respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C24H20ClN5O3
Mol. Weight :
461.90
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A potent, orally available, and brain-penetrating receptor interacting protein 1 (RIP1) kinase inhibitor with RIP1 pKi = 9.04, ER = 0.6, HLM (μL/min/mG) = <1.

References : Yoshikawa M. et al.: J. Med. Chem., 61(6), 2384-2409, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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