JNJ-28312141 hydrochloride

SI-8010

JNJ-28312141 hydrochloride, >98% (HPLC)

CAS No. : [1149939-55-8]

IUPAC Name : 4-Cyano-N-(5-(1-(dimethylglycyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl]-2-yl)-1H-imidazole-2-carboxamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : JNJ‑28312141 hydrochloride potently inhibits CSF‑1R (IC₅₀ = 0.69 nM) and reduces proliferation across multiple hematopoietic cancer cell lines. It also exhibits anti‑inflammatory activity in mouse arthritis models, making it a valuable tool for studying CSF‑1R‑mediated signaling and inflammation.

References : Illig C. R. et al.: J. Med. Chem., 54(22), 7860-83, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.