JNJ-54175446

SI-1250

JNJ-54175446, >98% (HPLC)

CAS No. : [1627902-21-9]

MDL No. : MFCD31556312

Synonyms : JNJ54175446

IUPAC Name : (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyrimidin-2-yl)-4-methyl-1,4-dihydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)-methanone

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
10MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
25MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
50MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
100MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
250MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
500MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
Note: JNJ-54175446 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : JNJ-54175446 is a potent and selective, brain penetrant P2X7 ion channel antagonist with _PIC₅₀ of 8.46 and 8.81 for hP2X7 and rP2X7, respectively.

References : Letavic A. M. et al.: J. Med. Chem., 60(11), 4559-4572, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.