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JNJ-63576253 HCl

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SL-7538

JNJ-63576253 HCl, >98% (HPLC)

CAS No. : [2110428-64-1]

IUPAC Name : 5-(8-Oxo-5-(6-(piperidin-4-yloxy)pyridin-3-yl)-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinonitrile hydrochloride

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Chemical Properites
Mol. Formula :
C23H21F3N6O2S . HCl
Mol. Weight :
538.97
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : JNJ-63576253 HCl is a clinical stage, next-generation androgen receptor (AR) antagonist for the treatment of castration-resistant prostate cancer (CRPC).

References : Zhang Z. et al.: J. Med. Chem., 64, 909-924, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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