JNJ-7706621

SI-7826

JNJ-7706621, >98% (HPLC)

CAS No. : [443797-96-4]

IUPAC Name : 4-((5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl)amino)benzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : JNJ‑7706621 potently inhibits CDK1 (IC₅₀ = 9 nM), CDK2 (IC₅₀ = 3 nM), Aurora‑A (IC₅₀= 11 nM), and Aurora‑B (IC₅₀ = 15 nM), reflecting its profile as a dual Aurora kinase and CDK inhibitor. This activity supports its use in studies of mitotic control and cell‑cycle checkpoint regulation.

References : Emanuel S. et al.: Cancer Res., 65(19), 9038-46, 2005; Huang S. et al.: Bioorg Med. Chem. Lett., 16(14), 3639-41, 2006; Seamon J. A. et al.: Mol. Cancer Ther., 5(10), 2459-67, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.