JNJ-78394355

SI-7923

JNJ-78394355, >98% (HPLC)

CAS No. : [2697112-33-5]

Synonyms : JNJ-4355

IUPAC Name : (Z)-1⁵-Chloro-9^6-fluoro-2¹-(2-(2-methoxyethoxy)ethyl)-1³,2³,6¹-trimethyl-1¹H,2¹H,6¹H-10-oxa-4-thia-1(4,1)-indola-2(4,5),6(3,5)-dipyrazola-9(3,1)-naphthalenacyclotridecaphane-1²-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : JNJ‑4355 potently inhibits MCL‑1 with a K_iof 18 pM and functions as a high‑quality chemical probe for dissecting MCL‑1–mediated survival pathways. Its strong target engagement underlies its demonstrated antitumor activity.

References : Jouffroy M. et al.: ACS. Catal., 12, 8380–8385, 2022; Rombouts J. F. et al.: Cancer Res., 82 (12), 2133, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.