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JPHM-2-167

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SI-7529

JPHM-2-167, >98% (HPLC)

CAS No. : [2924183-43-5]

IUPAC Name : 3-([1,1'-Biphenyl]-4-yl)-8-((3-methylpyridin-2-yl)methyl)-1-(pyrimidin-2-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione

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Chemical Properites
Mol. Formula :
C30H28N6O2
Mol. Weight :
504.59
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : JPHM‑2‑167 selectively inhibits PHD2 and PHD3 with sub‑micromolar to low‑micromolar potency, promoting HIF stabilization and downstream erythropoietic signaling. Its pharmacological profile supports its use in chronic kidney disease research.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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