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K812

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SI-6341

K812, >98% (HPLC)

CAS No. : [1355228-39-5]

IUPAC Name : N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-1-isopropyl-4-oxo-1,4-dihydroquinoline-3-carboxamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C30H27N3O5
Mol. Weight :
509.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : K812 potently and selectively inhibits ASK1 at low‑nanomolar concentrations and demonstrates in vivo neuroprotective activity. It reduces glial activation within the spinal cord and extends survival in SOD1‑G93A mice, making it a useful tool for investigating ASK1‑dependent mechanisms in ALS.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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