KB-0742 dihydrochloride

SI-7418

KB-0742 dihydrochloride, >98% (HPLC)

IUPAC Name : (1S,3S)-N1-(5-(Pentan-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine dihydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : KB‑0742 dihydrochloride selectively targets CDK9/cyclin T1 with low‑nanomolar potency (IC₅₀ = 6 nM) and maintains >50‑fold selectivity over other CDKs. Through inhibition of CDK9‑mediated transcriptional regulation, it exerts potent anti‑tumor effects, making it a valuable tool for studying CDK9‑driven malignancies.

References : Andre R. et al.: Cell Chem. Biol., S2451-9456(20), 30380-9, 2020; Freeman D. B. et al.: J. Med. Chem., 66(23), 15629-15647, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.