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Keap1-Nrf2-IN-3

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SI-6859

Keap1-Nrf2-IN-3, >98% (HPLC)

CAS No. : [2095066-47-8]

IUPAC Name : 5-((1S,2S)-2-(1-Methyl-1H-1,2,3-triazol-4-yl)cyclopropyl)-1-(3'-((R)-2-propylpiperidine-1-carbonyl)-[1,1'-biphenyl]-3-yl)-1H-pyrazole-4-carboxylic acid

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Chemical Properites
Mol. Formula :
C31H34N6O3
Mol. Weight :
538.65
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a KEAP1:NRF2 protein−protein interaction inhibitor, and with a Kd value of 2.5 nM for KEAP1 protein.

References : Norton D. et al.: J. Med. Chem., 64(21), 15949-15972, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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