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Ketoconazole sulfonic acid

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SL-4820

Ketoconazole sulfonic acid, >98%

Synonyms : Ketoconazole impurity 15

IUPAC Name : 2-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-5-(4-acetylpiperazin-1-yl)phenyl hydrogen sulfite

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5MGRequest A Quote
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We accept
Chemical Properites
Mol. Formula :
C26H28Cl2N4O7S
Mol. Weight :
611.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Ketoconazole, which is an inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase, used to treat certain serious fungal infections in the body.

References : Oliver W. R Jr. et al.: Proc. Natl. Acad. Sci., U S A, 98(9), 5306-5311, 2001; Eil C. et al.: Horm Metab Res, 24(8), 367-370, 1992; Forgue-Lafitte M. E. et al. Cancer Res, 52(24), 6827-6831, 1992; Gupta A. K. et al.: Br. J. Dermatol, 142(4), 758-765, 2000; Goeders N. E. et al.: Drug Alcohol Depend, 53(1), 67-77, 1998; Salphati L. et al.: Pharmacology, 56(6), 308-313, 1998.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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