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KO-947

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SI-7872

KO-947, >98% (HPLC)

CAS No. : [1695533-89-1]

IUPAC Name : 6-Benzyl-3-(pyridin-4-yl)-1,5,6,8-tetrahydro-7H-pyrazolo[4,3-g]quinazolin-7-one

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H17N5O
Mol. Weight :
355.4
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : KO‑947 selectively targets ERK1/2 with high potency and is used to investigate MAPK‑pathway–dependent tumor biology. Its activity profile highlights its relevance in models of MAPK‑dysregulated cancers.

References : Burrows F. et al.: Cancer Res., 77(13), 5168, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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