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KRN-633

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SL-361

KRN-633, >98%

CAS No. : [286370-15-8]

MDL No. : MFCD14155620

Synonyms : N-​[2-​Chloro-​4-​[(6,​7-​dimethoxy-​4-​quinazolinyl)oxy]phenyl]-​N'-​propyl-​urea

IUPAC Name : 1-(2-Chloro-4-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-propylurea

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
10MG125.00
Back Order  Estimated to ship on 04 October 2026
25MG145.00
Back Order  Estimated to ship on 04 October 2026
50MG255.00
Back Order  Estimated to ship on 04 October 2026
100MG255.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H21ClN4O4
Mol. Weight :
416.86
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Quinazoline urea derivative KRN-633 is a selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. KRN-633 was well tolerated and had no significant effects on body weight or the general health of the animals and useful in the treatment of solid tumors and other diseases that depend on pathologic angiogenesis.

References : Nakamura K. et. al.: Molecular Cancer Therapeutics, 3(12),1639, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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