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CAS No. : [286370-15-8]
MDL No. : MFCD14155620
Synonyms : N-[2-Chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N'-propyl-urea
IUPAC Name : 1-(2-Chloro-4-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-propylurea
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 10MG | 125.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | 145.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | 255.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | 255.00 | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H21ClN4O4 | Mol. Weight : 416.86 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Quinazoline urea derivative KRN-633 is a selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth. KRN-633 was well tolerated and had no significant effects on body weight or the general health of the animals and useful in the treatment of solid tumors and other diseases that depend on pathologic angiogenesis.
References : Nakamura K. et. al.: Molecular Cancer Therapeutics, 3(12),1639, 2004.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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