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KU-0063794

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SI-6454

KU-0063794, >98% (HPLC)

CAS No. : [938440-64-3]

IUPAC Name : (5-(2-((2S,6R)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C25H31N5O4
Mol. Weight :
465.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : KU‑0063794 selectively inhibits mTORC1 and mTORC2 with IC50 values of 10 nM, providing robust suppression of mTOR‑regulated growth and survival pathways in cellular models.

References : Garcia-Martinez et al.: Biochem. J., 421(1), 29-42, 2009; Collak F. K. et al.: J. Biol. Chem., 287(28), 23698-709, 2012; Haagensen E. J. et al.: Br. J. Cancer., 106(8), 1386-94, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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