KU-59403

SI-8169

KU-59403, >98% (HPLC)

CAS No. : [845932-30-1]

IUPAC Name : 3-(4-Methylpiperazin-1-yl)-N-(6-(6-morpholino-4-oxo-4H-pyran-2-yl)thianthren-2-yl)propanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : KU-59403 inhibits ATM with low‑nanomolar potency (IC₅₀ = 3 nM) and displays weak inhibition of DNA‑PK and PI3K (IC₅₀ ≈ 9–10 µM). Its selectivity makes it valuable for probing ATM‑specific signaling in DNA‑damage and repair studies.

References : Batey M. A. et al.: Mol. Cancer Ther., 12(6), 959-67, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.