L-38

SI-7381

L-38, >98% (HPLC)

CAS No. : [2956791-61-8]

Synonyms : NLRP3-IN-21

IUPAC Name : 2-Chloro-7-((5-(2-chloro-6-(trifluoromethyl)pyridin-3-yl)-1,3,4-oxadiazol-2-yl)methyl)-5-isopropylthieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-8(7H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This functions as an NLRP3 inflammasome inhibitor with demonstrable anti‑inflammatory effects. It attenuates NLRP3‑driven pyroptosis by suppressing gasdermin D processing, limiting ASC oligomer formation, and impairing NLRP3 inflammasome assembly, making it a useful tool for dissecting inflammasome‑mediated inflammatory pathways.

References : Li N. et al.: J. Med. Chem., 66(19), 13428-13451, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.