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L-Phenylalanyl-L-phenylalanine

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SL-7330

L-Phenylalanyl-L-phenylalanine, >98%

CAS No. : [2577-40-4]

MDL No. : MFCD00063154

Synonyms : H-Phe-Phe-OH

IUPAC Name : (S)-2-((S)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G15.00
Back Order  Estimated to ship on 20 September 2026
5G35.00
Back Order  Estimated to ship on 20 September 2026
10G65.00
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25G165.00
Back Order  Estimated to ship on 20 September 2026
100G625.00
Back Order  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C18H20N2O3
Mol. Weight :
312.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Bortezomib, which is a potent 20S proteasome inhibitor. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.

References : Adams J. et al.: Cancer Res., 59(11), 2615-2622, 1999; Boccadoro M. et al.: Cancer Cell Int., 5(1), 18, 2005; LeBlanc R. et al.: Cancer Res., 62(17), 4996-5000, 2002; Stein R. L. et al.: Biochemistry 35(13), 3899-3908, 1996; Hideshima T. et al.: Cancer Res., 61(7), 3071-3076, 2001, Mohammad A. Shahshahan et al.: Am J. Cancer Res., 1(7), 913-24, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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