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L-Thyroxine 4’-O-β-D-glucuronide

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SL-1263

L-Thyroxine 4’-O-β-D-glucuronide, >98%

CAS No. : [21462-56-6]

MDL No. : MFCD24386427

Synonyms : Thyroxine glucuronide

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Chemical Properites
Mol. Formula :
C21H19I4NO10
Mol. Weight :
952.99
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : L-Thyroxine 4’-O-β-D-glucuronide is a major metabolite of Thyroxine and glucuronide conjugate of Thyroxine formed via the glucuronidation of the phenyl hydroxyl group. L-Thyroxine is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

References : Tong Z. et al.: Drug Metab. Dispos., 35, 2203, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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