Lamivudine acid

SL-3422

Lamivudine acid, >98%

CAS No. : [173829-09-9]

Synonyms : Lamivudine EP impurity A

IUPAC Name : (2R, 5S)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid

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Applications : Lamivudine acid is an impurity of Lamivudine (Lamivudine EP impurity A), which is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS.

References : Shaw T. et al.: J. Viral Hepat., 6(2), 89-106, 1999; Colledge D. et al.: Hepatology 26(1), 216-225,1997; Merrill D. P. et al.: J. Infect Dis., 173(2), 355-364, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.