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Lamivudine (S)-sulfoxide

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Lamivudine (S)-sulfoxide, >98%

CAS No. : [160552-55-6]

Synonyms : Lamivudine EP impurity G; Lamivudine impurity G

IUPAC Name : 4-Amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

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Chemical Properites
Mol. Formula :
C8H11N3O4S
Mol. Weight :
245.26
Appearance :
White solid
Melting Point :
Not available
Solubility :
H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : Lamivudine (S)-sulfoxide is a meatbolite of Lamivudine (Lamivudine EP impurity G), which is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS.

References : Shaw T. et al.: J. Viral Hepat., 6(2), 89-106, 1999; Colledge D. et al.: Hepatology., 26(1), 216-225, 1997; Merrill D. P. et al.: J. Infect Dis., 173(2), 355-364, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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