Landiolol hydrochloride

SL-10776

Landiolol hydrochloride, >98%

CAS No. : [144481-98-1]

Synonyms : ONO-1101 hydrochloride

IUPAC Name : ((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((S)-2-hydroxy-3-((2-(morpholine-4-carboxamido)ethyl)amino)propoxy)phenyl)propanoate hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Landiolol hydrochloride is a highly selective, ultra-short-acting β1 adrenergic receptor blocker that lowers heart rate and myocardial oxygen demand. It inhibits TNF-α-induced mitochondrial oxygen consumption and reactive oxygen species in sepsis models, helping prevent renal injury. Landiolol hydrochloride minimally affects cardiac ion channels and has a weak negative inotropic effect. It is used for perioperative tachycardia control and in studies on sepsis-related acute kidney injury.

References : Tomihari M. et al.: Biomed Res., 45(6), 253-259, 2024; Kiyonaga N. et al.: Shock 52(5), e117-e123, 2019; Shibata S. et al.: J. Pharmacol Sci., 118(2), 255-65, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.