Lanraplenib monosuccinate

SI-6322

Lanraplenib monosuccinate, >98% (HPLC)

CAS No. : [1800046-97-2]

Synonyms : GS-9876 monosuccinate

IUPAC Name : 6-(6-Aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine monosuccinate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Lanraplenib monosuccinate is a potent, selective SYK inhibitor (IC₅₀ = 9.5 nM) that blocks GPVI‑dependent platelet SYK signaling without affecting bleeding time. Its pharmacological profile supports its use in studies of inflammatory pathways and immune‑driven disease mechanisms.

References : Di Paolo J. et al.: Annals of the Rheumatic Diseases 75, 443-444, 2016; Clarke A. S. et al.: Thromb. Res., 170, 109-118, 2018; Kivitz A. J. et al.: Arthritis Rheumatol., 70 (10), 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.