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SI-7994

Lartesertib, >98% (HPLC)

CAS No. : [2495096-26-7]

Synonyms : M-4076; ATM inhibitor-5

IUPAC Name : 8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one

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Chemical Properites
Mol. Formula :
C23H21FN6O3
Mol. Weight :
448.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Lartesertib potently inhibits ATM and reduces the growth of hematopoietic cancer cell lines. In dual inhibition with Tuvusertib, it drives tumor‑cell killing and activates immune signaling, resulting in pronounced antitumor effects.

References : Mukker J. K. et al.: Cancer Research., 84(6), 7186-7186, 2024; Laaber K. et al.: Cancer Research., 84(6), 5617-5617, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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