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LCL-161

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SI-5079

LCL-161, >98% (HPLC)

CAS No. : [1005342-46-0]

MDL No. : MFCD23160049

IUPAC Name : (S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide

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Chemical Properites
Mol. Formula :
C26H33FN4O3S
Mol. Weight :
500.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LCL161 is an oral inhibitor of apoptosis proteins (IAPs) antagonist and it has anti-tumors activity.

References : Chen K. F. et al.: Biochem Pharmacol., 84(3), 268-277, 2012; Dhuria S. et al.: J. Clin Pharmacol., 53(6), 642-653, 2013; Infante J. R. et al.: J. Clin Oncol. 32(28), 3103-3110, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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