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LDN-192960

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SI-7464

LDN-192960, >98% (HPLC)

CAS No. : [184582-62-5]

IUPAC Name : 3-((2,7-Dimethoxyacridin-9-yl)thio)propan-1-amine

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Chemical Properites
Mol. Formula :
C18H20N2O2S
Mol. Weight :
328.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LDN‑192960 inhibits Haspin (IC50 = 10 nM) and DYRK2 (IC50 = 48 nM), enabling targeted interrogation of mitotic kinase function and related signaling mechanisms.

References : Cuny G. D. et al.: Bioorg. Med. Chem. Lett., 20(12), 3491-4, 2010; Kestav K. et al.: Curr. Med. Chem., 24(21), 2276-2293, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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