LDN-214117

SI-6387

LDN-214117, >98% (HPLC)

CAS No. : [1627503-67-6]

IUPAC Name : 1-(4-(6-Methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenyl)piperazine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LDN‑214117 selectively inhibits ALK2 with low‑nanomolar potency and exhibits good CNS exposure and low cytotoxicity. It also suppresses BMP6‑driven signaling. Its pharmacological profile makes it a valuable tool for investigating ALK2/BMP pathway dysregulation in FOP and DIPG models.

References : Mohedas H. A. et al.: J. Med. Chem., 57(19), 7900-15, 2014; Mihajlović J. et al.: J. Cancer Res. Clin. Oncol., 145(11), 2675-2687, 2019; Carvalho D. et al.: Commun. Biol., 2, 156, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.