LDN-27219

SI-8167

LDN-27219, >98% (HPLC)

CAS No. : [312946-37-5]

IUPAC Name : 2-((4-Oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LDN‑27219 inhibits human TG2 with sub‑micromolar potency (IC₅₀= 0.6 µM) through a reversible, slow‑binding mechanism. It produces antihypertensive and vasodilatory effects, enabling its application in cardiovascular biology and disease research.

References : Case A. et al.: Biochemistry, 46(4), 1106-15, 2007; Pinilla E. et al.: Hypertension, 77(1), 216-227, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.