Lenacapavir

SL-10816

Lenacapavir, >98%

CAS No. : [2189684-44-2]

Synonyms : GS-6207

IUPAC Name : N-((S)-1-(3-(4-Chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
250MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
500MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
1G	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : Lenacapavir is an inhibitor of the HIV-1 capsid. It demonstrates anti-HIV activity with an EC50 of 100 pM in MT-4 cells, and shows a mean EC50 of 50 pM (ranging from 20 to 160 pM) across 23 HIV-1 clinical isolates from various subtypes in peripheral blood mononuclear cells (PBMCs). As a click chemistry reagent, Lenacapavir features an Alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compounds containing azide groups.

References : Singh K. et al.: Front Microbiol., 10, 1227, 2019; John O. L. et al.: Nature, 584(7822), 614-61, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.