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Leniolisib-d5

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SI-7085

Leniolisib-d5, >98% (HPLC)

Synonyms : CDZ-173-d5

IUPAC Name : (S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one-2,2,3,3,3-d5

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H20D5F3N6O2
Mol. Weight :
455.5
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Leniolisib‑d5 is a deuterium-labelled version of Leniolisib. This can be used as an analytical labelled reference standard. Also, this can be used in pharmacokinetic and mechanistic studies. Leniolisib is a selective PI3Kδ inhibitor with strong activity in models of PI3Kδ‑mediated immunodeficiency.

References : Edward M. R. et al.: 53(2), 211-216, 2019; Rao V. et al.: Blood, 130(21), 2307-2316, 2017; Hoegenauer K. et al.: ACS Med. Chem. Lett., 8(9), 975-980, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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