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Leniolisib phosphate

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SI-7086

Leniolisib phosphate, >98% (HPLC)

CAS No. : [1354691-97-6]

Synonyms : CDZ-173 phosphate

IUPAC Name : (S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one phosphate

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Chemical Properites
Mol. Formula :
C21H25F3N6O2 • H3PO4
Mol. Weight :
548.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Leniolisib phosphate serves as a selective PI3Kδ inhibitor and a prodrug of Leniolisib. It targets PI3Kδ‑driven immune dysregulation and has potential utility in the treatment of immunodeficiency disorders.

References : Edward M. R. et al.: 53(2), 211-216, 2019; Rao V. et al.: Blood, 130(21), 2307-2316, 2017; Hoegenauer K. et al.: ACS Med. Chem. Lett., 8(9), 975-980, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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