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CAS No. : [417716-92-8]
MDL No. : MFCD16038644
Synonyms : E7080
IUPAC Name : 4-(3-Chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | 50.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | 70.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | 150.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | 225.00 | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C21H19ClN4O4 | Mol. Weight : 426.85 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Lenvatinib is an oral, multi-targeted tyrosine kinase inhibitor with IC50s of 4 and 5.2 nM for VEGFR2(KDR) and VEGFR3(Flt-4), respectively. Lenvatinib is less potent against VEGFR1/Flt-1 and shows approximately 10-fold selectivity for VEGFR2/3 over FGFR1, PDGFRα/β.
References : Matsui J. et al.: Int. J. Cancer 122(3), 664-671, 2008; Matsui J. et al.: Clin Cancer Res., 14(17), 545, 2008; Glen H. et al.: BMC Cancer 11, 309, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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