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Lerociclib

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SI-7123

Lerociclib, >98% (HPLC)

CAS No. : [1628256-23-4]

Synonyms : G1T38

IUPAC Name : 2'-((5-(4-Isopropylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one

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Chemical Properites
Mol. Formula :
C26H34N8O
Mol. Weight :
474.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Lerociclib selectively targets CDK4/6 with low‑nanomolar potency (IC50 = 1–2 nM), making it a valuable tool for probing CDK‑dependent G1‑phase cell‑cycle control.

References : Bisi J. E. et al.: Oncotarget., 8(26), 42343-42358, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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