Letrozole

SL-6483

Letrozole, >98%

CAS No. : [112809-51-5]

MDL No. : MFCD00866241

Synonyms : CGS-20267

IUPAC Name : 4,4'-((1H-1,2,4-Triazol-1-yl)methylene)dibenzonitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	50.00		In Stock	Estimated to ship on 20 September 2026
5G	150.00		In Stock	Estimated to ship on 20 September 2026
10G	225.00		In Stock	Estimated to ship on 20 September 2026
25G	450.00		In Stock	Estimated to ship on 20 September 2026
100G	980.00		In Stock	Estimated to ship on 20 September 2026

Applications : Letrozole is a third generation inhibitor of aromatase with IC₅₀ of 0.07-20 nM in cell-free assays. It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies.

References : Haynes B. P. et al.: J. Steroid Biochem Mol Biol., 87(1), 35-45, 2003; Bhatnagar A. S. et al.: J. Steroid Biochem Mol Biol., 37(6), 1021-1027, 1990; Mitropoulou T. N. et al.: Int. J. Cancer., 104(2), 155-160, 2003; Dellapasqua S. et al.: Expert Opin Drug Metab Toxicol., 6(2), 251-259, 2010; Lee K. et al.: Int J Cancer., 62(3), 297-302, 1995; Steele R. E. et al.: Steroids, 50(1-3), 147-161, 1987.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.