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Levomepromazine

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SL-10858

Levomepromazine, >98%

CAS No. : [60-99-1]

Synonyms : Methotrimeprazine

IUPAC Name : (R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H24N2OS
Mol. Weight :
328.47
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Levomepromazine is an orally active antipsychotic that induces Ca2+ release by inhibiting the SERCA pump. It acts as an antagonist on dopamine, cholinergic, serotonin, and histamine receptors, and can trigger ER stress and autophagy. Additionally, it has antiviral, anti-inflammatory, neuroprotective, analgesic, sedative, and anti-injurious properties. Levomepromazine is used in studying psychiatric disorders and for relieving nausea and vomiting.

References : Prajapat S. K. et al.: EMBO Mol Med., 16(1), 185-217, 2024; Petts H. V. et al.: Br. J. Anaesth., 55(5), 437-41, 1983; Cox L. et al.: Cochrane Database Syst Rev., (11), CD009420, 2015; Sivaraman P. et al.: Cochrane Database Syst Rev., (10), CD007779, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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