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Levothyroxine methoxyphenoxy aldehyde impurity

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SL-1276

Levothyroxine methoxyphenoxy aldehyde impurity, >98%

CAS No. : [69240-57-9]

MDL No. : MFCD30720435

Synonyms : 3,5-Diiodo-4-(p-methoxyphenoxy)benzaldehyde

IUPAC Name : 3,5-Diiodo-4-(4-methoxyphenoxy)benzaldehyde

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Chemical Properites
Mol. Formula :
C14H10I2O3
Mol. Weight :
480.04
Appearance :
Off-white solid
Melting Point :
120-122oC (lit.)
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of L-Thyroxine, which is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

References : Arici M. et al.: Endocr J. 65(3), 317, 2018; Corriveau S. et al.: J. Clin Transl Endocrinol. 2(4),144, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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