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Levothyroxine-N-lactoside adduct

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Levothyroxine-N-lactoside adduct, >98%

IUPAC Name : (S)-2-(((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C27H31I4NO14
Mol. Weight :
1101.16
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a lactoside adduct of Levothyroxine, which is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

References : Arici M. et al.: Endocr J. 65(3), 317, 2018; Corriveau S. et al.: J. Clin Transl Endocrinol., 2(4),144, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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