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Lincomycin-2,4 -phosphate

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Lincomycin-2,4 -phosphate, >98%

IUPAC Name : (2S,4R)-N-((1R,2R)-1-((1R,5R,6R,8R,9S)-3,9-Dihydroxy-8-(methylthio)-3-oxido-2,4,7-trioxa-3-phosphabicyclo[3.3.1]nonan-6-yl)-2-hydroxypropyl)-1-methyl-4-propylpyrrolidine-2-carboxamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C18H33N2O8PS
Mol. Weight :
468.5
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a phosphorylated form of the lincosamide antibiotic Lincomycin, which affects protein, RNA, and DNA synthesis in the mycelium of the lincomycin-producing organism, Act. Roseolus. Lincomycin mainly inhibits protein production in Gram-positive bacteria and also has some effect on Gram-negative bacteria. It acts by attaching to the 50S subunit of bacterial ribosomes, interfering with aminoacyl-tRNA binding and disrupting the transpeptidation process.

References : Griaznova N. S. et al.: Antibiotiki., 25(4), 250-256, 1980; Hummel H. W. et al.: Mol Gen Genet., 169(3), 345-347, 1979; Champney W. S. et al.: Curr Microbiol., 41(2), 126-135, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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