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Linrodostat

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SI-5068

Linrodostat, >98% (HPLC)

CAS No. : [1923833-60-6]

Synonyms : BMS-986205; ONO-7701

IUPAC Name : (R)-N-(4-Chlorophenyl)-2-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide

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Chemical Properites
Mol. Formula :
C24H24ClFN2O
Mol. Weight :
410.92
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Linrodostat is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers.

References : Richards T. et al.: Oncotarget., 9(56), 30814-30820, 2018; Lillian L. Siu et al.: Cancer Res., 77 (13 Suppl), 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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