Liothyronine (R)-isomer impurity

SL-9594

Liothyronine (R)-isomer impurity, >98%

CAS No. : [1393257]

Synonyms : Levothyroxine D-triiodo thyronine; D-Triiodothyronine; 3,5,3'-Triiodo-D-thyronine

IUPAC Name : (R)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid

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Applications : This is an opposite enantiomer and impurity of Levothyroxine, which is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).

References : Arici M. et al.: Endocr J. 65(3), 317, 2018; Corriveau S. et al.: J. Clin Transl Endocrinol., 2(4),144, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.